Shelf Pure
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Dark spot pick · #34 skin Generated scene, not a product photo
La Roche-Posay · Skin · Serums

La Roche-Posay Mela B3 Dark Spot Serum With Melasyl + Niacinamide

The maker's newer ingredient, Melasyl, with 10% niacinamide, sold to visibly reduce the look of dark spots. Some owners see fading; many report no change after months, and the perfume is strong.

30 mlSerumMelasyl (2-mercaptonicotinoyl glycine)NiacinamideHyaluronic acidScented
$44.99 MSRPAmazon price not shown
Check price on Amazon →

Amazon link · we earn a commission if you buy · $44.99 MSRP · Amazon price not shown · verified Nov 1, 2026. More stores appear here as each affiliate program approves the site.

Buy it if

  • You want Melasyl and 10% niacinamide in one serum
  • You want to try for a more even look on stubborn marks
  • You do not mind a scented serum

Walk past if

  • You want a sure result; owners report no change after months
  • You react to fragrance; the list has it and a red dye
  • You want it cheap; the $44.99 MSRP buys 30 ml

What's in it

The ingredients that do the work, from the maker’s label.

Melasyl (2-mercaptonicotinoyl glycine)NiacinamideHyaluronic acid

Niacinamide guide →Sulfate-free →

Worth knowing: contains fragrance.

Full ingredient list, from the maker

AQUA / WATER / EAU, DIMETHICONE, NIACINAMIDE, GLYCERIN, PROPYLENE GLYCOL, POLYSILICONE-11, SILICA, BIS-PEG/PPG-16/16 PEG/PPG-16/16 DIMETHICONE, CYSTOSEIRA TAMARISCIFOLIA EXTRACT, 2-MERCAPTONICOTINOYL GLYCINE, PEG-20 METHYL GLUCOSE SESQUISTEARATE, SODIUM HYALURONATE, SODIUM HYDROXIDE, SODIUM THIOSULFATE, CARNOSINE, POLOXAMER 338, AMMONIUM POLYACRYLOYLDIMETHYL TAURATE, DIPOTASSIUM GLYCYRRHIZATE, CAPRYLIC/CAPRIC TRIGLYCERIDE, CAPRYLOYL SALICYLIC ACID, CAPRYLYL GLYCOL, CITRIC ACID, TRISODIUM ETHYLENEDIAMINE DISUCCINATE, XANTHAN GUM, PENTYLENE GLYCOL, OCTYLDODECANOL, RETINYL PALMITATE, TOCOPHEROL, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE, PHENOXYETHANOL, CI 17200 / RED 33, PARFUM / FRAGRANCE

Known issue

Many owners see no change in dark spots after months, some report darker spots or irritation, and others cannot stand the perfume.Walmart and Ulta reviews

What owners say

Filled by the research pass: two or three owner reports from named venues, each linked, each with the date it was read.

If it's not right

The Ordinary Niacinamide 10% + Zinc 1%$6 MSRPTen percent niacinamide with zinc PCA in a water-based serum. Cheap enough to try, and sticky enough that owners complain about what it does under the next layer.CeraVe Moisturizing CreamNo maker list price for this sizeThree ceramides, cholesterol, hyaluronic acid and petrolatum in a thick cream for face and body. The plain standard for dry skin, developed with dermatologists according to the maker.

Sources

  1. Maker page: ingredient list, 30 ml list price, 10% niacinamide and dark spot claims, safety statements.
  2. Walmart reviews, 1 fl oz: no change after months, darker spots for a few, one severe reaction, and a strong perfume smell.
  3. Ulta reviews, 1 oz: no changes after most of a bottle, darker discoloration for one owner, and an awful odor for another.

Ingredient lists from the maker's label, not our measurements.